grade 1: Introduction to the Biology of Cancer

Over 500,000 people in the United States and over 8 million people worldwide are dying every year from cancer. As people live longer, the incidence of cancer is rising worldwide and the disease is expected to strike over 20 million people annually by 2030. This open course is designed for people who would like to develop an understanding of cancer and how it is prevented, diagnosed, and treated.

The course introduces the molecular biology of cancer (oncogenes and tumor suppressor genes) as well as the biologic hallmarks of cancer. The course also describes the risk factors for the major cancers worldwide, including lung cancer, breast cancer, colon cancer, prostate cancer, liver cancer, and stomach cancer. We explain how cancer is staged, the major ways cancer is found by imaging, and how the major cancers are treated. In addition to the core materials, this course includes two Honors lessons devoted to cancers of the liver and prostate. Upon successful completion of this course, you will be able to: – Identify the major types of cancer worldwide. (Lecture 1) – Describe how genes contribute to the risk and growth of cancer. (Lecture 2) – List and describe the ten cellular hallmarks of cancer. (Lecture 3) – Define metastasis, and identify the major steps in the metastatic process. (Lecture 4) – Describe the role of imaging in the screening, diagnosis, staging, and treatments of cancer. (Lecture 5) – Explain how cancer is treated. (Lecture 6) We hope that this course gives you a basic understanding of cancer biology and treatment. The course is not designed for patients seeking treatment guidance – but it can help you understand how cancer develops and provides a framework for understanding cancer diagnosis and treatment.

grade 2: Understanding Cancer Metastasis

Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030.

Everyone has been, or will be touched by cancer in some way during their lifetime. Thanks to years of dedication and commitment to research we’ve made enormous advances in the prevention and treatment of cancer, But there is still a lot of work to be done. In this course, physicians and scientists at the Johns Hopkins School of Medicine explain how cancer spreads or metastasizes. We’ll describe the major theories of metastasis and then describe the biology behind the steps in metastasis. The course also describes the major organs targeted by metastasis and describes how metastases harm the patient.

grade 3: Understanding Prostate Cancer

Welcome to Understanding Prostate Cancer. My name is Ken Pienta, Professor of Urology and Oncology at the Johns Hopkins School of Medicine. I have been studying prostate cancer and treating patients with prostate cancer for over 25 years.

Over 1,000,000 men worldwide and 230,000 men in the United States are diagnosed with prostate cancer every year. Three hundred thousand men worldwide and 30,000 men in the US are dying from prostate cancer every year. As people live longer, the incidence of prostate cancer is rising worldwide and prostate cancer continues to be a major health problem. Thanks to years of dedication and commitment to research we’ve made enormous advances in the treatment of prostate cancer, But there is still a lot of work to be done. In this Understanding Prostate Cancer course, I will provide an introduction to the biology of prostate cancer as well as how it is identified and treated at various stages of the disease. I’ve put together this course in order to introduce you to the essentials of prostate cancer. By the time you finish this course you’ll be able to  Define risk factors for prostate cancer  Understand current prostate cancer screening guidelines  Understand prostate cancer staging  Understand treatments for localized prostate cancer  Understand treatments for advanced prostate cancer  Understand treatments to alleviate the symptoms caused by prostate cancer This Understanding Prostate Cancer Course should be helpful to anyone who wants to develop a deeper understanding of prostate cancer biology and treatment. It should be useful to students who are interested in a deeper understanding of the science of cancer. It should also be helpful to health care providers, data managers, and educators who wish to develop a better understanding of prostate cancer and how it affects individuals. The course is not designed for patients seeking treatment guidance. For those of you who might be thinking about a career in cancer research or patient care, I hope this course will inspire you to pursue that path! The course is divided into five modules organized to facilitate learning. I’m glad that you decided to join this course. I hope that you will develop a basic understanding of prostate cancer. I hope that it will help you in whatever field you work. If you are a student, I hope that what you learn here will help you begin a career in cancer biology research and contribute to the worldwide effort to save lives.